Improve fermentation
Control the metabolic pathways of your production microorganisms.
We can help you to make your fermentation process to deliver the ingredients you want.
The latest genome sequencing technology allows fast and cheap sequencing of genomes of food grade microbes. For strain and fermentation process improvement you can translate genome sequence data into a metabolic model.
Together with a NIZO expert, in a one-day-session, you will use existing models of relevant lactic acid bacteria to discover the possibilities of genome scale metabolic modelling. You will get hands-on experience in metabolic flux analysis and visualisation of gene-expression data on metabolic maps. This activity will show you how to pinpoint metabolic bottlenecks and identify genes crucial for growth on alternative substrates.
Deliverables:
- You will learn how we construct metabolic models from raw genome sequence data for process optimisation.
- You will see how metabolic modelling is applied to optimise growth of fermentative microbes.
- Together with you, we will interpret the results and discuss the possibilities for building a metabolic model of your own production microorganism.
Prepare your visit by filling in the form (button [Start now]). Your host will contact you to agree with you on the program of the day and which models to use.
Want something more?
If the Quick scan doesn't meet your needs, we can offer you a Full scan.
