In-vivo trials

Proof-of-principle

Before deciding on a clinical study, it is useful to obtain first proof of the efficacy of your ingredient. With our large array of in-vivo models we can assist you in proof-of-principle studies. Read more in our leaflets on Biomarkers for Gut Health and Immune Defense and In vitro cell culture models.

NIZO options

NIZO food research has developed various research models to evaluate whether your product or ingredient can beneficially affect gut or respiratory health. The unique gut challenge models include the following: ETEC, Helicobacter, Listeria and Salmonella challenge studies. Gut integrity models include intestinal permeability, chronic inflammation (DSS, TNBS and HLA-B27) and colon carcinogenesis. To verify whether your product or ingredient beneficially affects respiratory health we have developed an Influenza model.