Getting from small scale trials and experiments to full-scale production can be quite a challenge. Lab conditions can differ greatly from actual production in terms of the conditions affecting the product (e.g. temperature distributions and pressure). To ensure a successful scale-up trajectory, NIZO offers varying tools in terms of multi-scale equipment for validation, and modelling for experimental design and process dimensioning. One such an example in production is heat treatment. To ensure a safe product with adequate shelf-life, heat treatment is the most reliable and most validated method. To tailor this to your situation, our experts on microbial inactivation and process-product interactions evaluate your process using in-house modelling tools. For validation, we have a large range of heat treatment equipment available, both on pilot scale from 100-10.000 L/h, and on lab scale from microliters to liters.