Personal Care & Pharma

Within personal care a growing trend is the use of natural ingredients. Numerous companies have strengthened their global presence in the natural cosmetics industry. In addition, personal care companies are focusing increasingly on the role of the microbiome in for example skin care – especially now that evidence is growing for the beneficial contribution of microorganisms to prevention and treatment of skin disorders. At NIZO we have a strong track record in modulation of such microbiomes.

Also in the pharmaceutical industry large companies and capital investors are increasingly investing in the microbiome domain. Initiatives are being set up to elucidate the role of the microbiome in metabolic diseases, cardiovascular diseases and cancer. At NIZO we specialise in modulation of microbiota related to several of these diseases. Our unique collaboration with Medimetrics with regard to the IntelliCap® technology for sampling the small intestine underlines our expertise in this field.

Personal Care & Pharma Publications

  • Haskel (US), J. Monk (US), N. Khan (US), K. Burseg (NL), P.M.T. de Kok (NL), A. Stijnman (NL), “System and method for making an oral care formulation”, Colgate-Palmolive Company & Nizo Food Research B.V, Patent Pub. No.: WO/2015/009876, International Application No.: PCT/US2014/046925, Publication Date:  22.01.2015 International Filing Date:  16.07.2014.
  • Zeeuwen PL, Boekhorst J, van den Bogaard EH, de Koning HD, van de Kerkhof PM, Saulnier DM, van Swam II, van Hijum SA, Kleerebezem M, Schalkwijk J, Timmerman HM. Microbiome dynamics of human epidermis following skin barrier disruption. Genome Biol. 2012 Nov 15;13(11):R101. doi: 10.1186/gb-2012-13-11-r101. PubMed PMID: 23153041; PubMed Central PMCID: PMC3580493.
  • Cremers AJ, Zomer AL, Gritzfeld JF, Ferwerda G, van Hijum SA, Ferreira DM, Shak JR, Klugman KP, Boekhorst J, Timmerman HM, de Jonge MI, Gordon SB, Hermans PW. The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition. Microbiome. 2014 Dec 15;2:44. doi: 10.1186/2049-2618-2-44. PubMed PMID: 25671106; PubMed Central PMCID: PMC4323220.
  • Zeeuwen PL, Ederveen TH, van der Krieken DA, Niehues H, Boekhorst J, Kezic S, Hanssen DA, Otero ME, van Vlijmen-Willems IM, Rodijk-Olthuis D, Falcone D, van den Bogaard EH, Kamsteeg M, de Koning HD, Zeeuwen-Franssen ME, van Steensel MA,  Kleerebezem M, Timmerman HM, van Hijum SA, Schalkwijk J. Gram-positive anaerobe cocci (GPAC) are underrepresented in the microbiome of filaggrin-deficient human  skin. J Allergy Clin Immunol. 2016 Oct 7. pii: S0091-6749(16)31117-4. doi:10.1016/j.jaci.2016.09.017. [Epub ahead of print] PubMed PMID: 27725187.
  • Cassard L, Lalanne AI, Garault P, Cotillard A, Chervaux C, Wels M, Smokvina T, Daëron M, Bourdet-Sicard R.  Individual strains of Lactobacillus paracasei differentially inhibit human basophil and mouse mast cell activation. Immun Inflamm Dis. 2016 Jul 7;4(3):289-99. doi: 10.1002/iid3.113. PubMed PMID: 27621812; PubMed Central PMCID: PMC5004284.
  • Martino ME, Bayjanov JR, Caffrey BE, Wels M, Joncour P, Hughes S, Gillet B, Kleerebezem M, van Hijum SA, Leulier F. Nomadic lifestyle of Lactobacillus plantarum revealed by comparative genomics of 54 strains isolated from different habitats. Environ Microbiol. 2016 Jul 16. doi: 10.1111/1462-2920.13455. [Epub ahead of print] PubMed PMID: 27422487.

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